FOLD AS YOU GO

 MONOTOPIC PHOSPHOGLYCOSYL TRANSFERASES SET SAIL

                                                                  C&E NEWS                                                 F1000PRIME

 
"Membrane Association of Monotopic Phosphoglycosyl Transferase Underpins Function” Ray, L. C.; Das, D.; Entova, S.; Lukose, V.; Lynch, A. J.; Imperiali, B.; Allen, K. N.  Nature Chem. Biol .  2018 ,  14 , 538-541. doi: 10.1038/s41589-018-0054-z.

"Membrane Association of Monotopic Phosphoglycosyl Transferase Underpins Function” Ray, L. C.; Das, D.; Entova, S.; Lukose, V.; Lynch, A. J.; Imperiali, B.; Allen, K. N. Nature Chem. Biol. 2018, 14, 538-541. doi: 10.1038/s41589-018-0054-z.

 

NUCLEOSIDES ON DEMAND

“Facile Solid-Phase Synthesis and Assessment of Nucleoside Analogs as Inhibitors of Bacterial UDP-Sugar Processing Enzymes” Madec, A. G. M.; Schocker, N. S.; Sanchini, S.; Myratgeldiyev, G.; Das, D.; Imperiali, B.  ACS Chem. Biol.  2018 ,  13 , 2542-2550.

“Facile Solid-Phase Synthesis and Assessment of Nucleoside Analogs as Inhibitors of Bacterial UDP-Sugar Processing Enzymes” Madec, A. G. M.; Schocker, N. S.; Sanchini, S.; Myratgeldiyev, G.; Das, D.; Imperiali, B. ACS Chem. Biol.2018, 13, 2542-2550.

EVERYTHING YOU ALWAYS WANTED TO KNOW ABOUT……!

“Monotopic Membrane Proteins Join the Fold”, Allen, K.N.; Entova,, S.E.; Ray, L.C.; Imperiali, B.,  Trends Biochem. Sci.   2019 ,  44 , 7-20.

“Monotopic Membrane Proteins Join the Fold”, Allen, K.N.; Entova,, S.E.; Ray, L.C.; Imperiali, B., Trends Biochem. Sci. 2019, 44, 7-20.

PING PONG ANYONE?!

"Analysis of a Dual Domain Phosphoglycosyl Transferase Reveals a Ping-Pong Mechanism with a Covalent Enzyme Intermediate", Das, D.; Kuzmic, P.; Imperiali, B.  Proc. Natl. Acad. Sci. U.S.A.   2017 , 114 , 7019-7024. PMCID: PMC5502628.

"Analysis of a Dual Domain Phosphoglycosyl Transferase Reveals a Ping-Pong Mechanism with a Covalent Enzyme Intermediate", Das, D.; Kuzmic, P.; Imperiali, B. Proc. Natl. Acad. Sci. U.S.A. 2017,114, 7019-7024. PMCID: PMC5502628.

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