OUR FIRST CRYO-EM STRUCTURE! HOMODIMERIC WbaP - A LARGE PGT IN A SMALP NANOPARTICLE
“Mapping the Architecture of the Initiating Phosphoglycosyl Transferase from S. enterica O-Antigen Biosynthesis in a Liponanoparticle” Dodge, G.J.; Anderson, A.J.; He, Y.; Liu, B.; Viner, R.; Imperiali, B. 2024 eLIFE in press.
“BACK TO BAC” IN THE BACILLUS SUBTILIS BIOFILM
“Defining Early Steps in B. subtilis Biofilm Biosynthesis” Arbour, C.A.; Nagar, R.; Bernstein, H.M.; Ghosh, S.; Al-Sammarrie, Y.; Dorfmueller, H.C.; Ferguson, M.A.J.; Stanley-Wall, N.R.; Imperiali, B. mBio, 2023, e0094823.
IT’S ALL IN THE LINKER!
“Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies” Seebald, L.M.a; Haratipour, P.b; Jacobs, M.R.b; Bernstein, H.M.a; Kashemirov, B.A.b; McKenna, C.E.b; Imperiali, B.a J. Am. Chem. Soc. 2024, 146, 3220-3229 (doi.org/10.1021/jacs.3c11402).
https://pubs.acs.org/articlesonrequest/AOR-F9FIV2NWYIF7ZP938AZ9
MIND THE GAP WITH mGAPS!
“Human oral lectin ZG16B acts as a cell wall polysaccharide probe to decode host-microbe interactions with oral commensals ” Ghosh, S. et al, PNAS USA 2023 in press
WHAT’S IN THE (AROMATIC) BOX?
“Co-Conserved Sequence Motifs are Predictive of Substrate Specificity in a Family of Monotopic Phosphoglycosyl Transferases” Anderson, A.J.; Dodge, G.J.; Allen, K.N.; Imperiali, B. 2023, Protein Science, in press.
GLYCAN BINDING PROTEINS BY DIRECTED EVOLUTION - NEW TOOLS FOR GLYCAN BIOLOGY”!
“Engineered Glycan-Binding Proteins for Recognition of the TF Antigen and Diverse Hexose Disaccharides” Ward, E.M.; Zamora, C.Y.; Schocker, N.S.; Ghosh, S,; Kizer, M.E.; Imperiali, B.; ACS Chem. Biol. 2023, 18, 70-80.
INVESTIGATING MEMBRANE PROTEINS VIA AN EXPEDITED STRATEGY!
A Strategic Approach for Fluorescence Imaging of Membrane Proteins in a Native-Like Environment” Swiecicki, J-M. Santana, J. Imperiali, B. Cell Chem. Biol. 2020 27, 1-7.
