Imperiali Lab Alumni
Dr. Sonta Entova (Ph.D. 2019) Thesis title:Structure-Function Relationships in Monotonic Phosphoglycosyl Transferases
Dr. Amael Madec (Postdoctoral Associate 2015-2018)
Research Scientist, Center for the Development of Therapeutic, Broad Institute, Cambridge MA
Dr Nate Schocker (Postdoctoral Associate 2016-2018)
Research Scientist, Optimvia, Houston, TX
Dr. Debasis Das (Postdoctoral Associate 2014-2018)
Assistant Professor of Chemistry, Indian Institute of Science. Bangalore India
Dr. Julie Silverman (Postdoctoral Associate 2013-2017)
Senior Scientist, Cell Biology and Protein Engineering,, Kanyos Bio, Cambridge, MA.
Dr. Joris DeSchutter (Postdoctoral Associate 2013-2016)
Life Sciences Consultant, Putnam Associates, Cambridge, MA.
Dr. Monika Musial-Siwek (Postdoctoral Associate 2013-2016)
Senior Scientist, Pfizer, Cambridge, MA.
Dr. Vinita Lukose (Ph.D. 2015)
Thesis title: “Priming and Processing Glycosyltransferases in Bacterial N-linked Glycosylation Pathways”
Head of New Product Introduction, String Bio Pvt. Ltd. Bengaluru, Kamataka, India.
Dr. Maria (Marthe) Walvoort (Postdoctoral Associate 2012-2015)
Assistant Professor, University of Groningen, Groningen, The Netherlands.
Dr. Garrett Whitworth (Postdoctoral Associate 2011-2015)
Environmental Consultant and Data Analyst, Whitworth Environmental, Vancouver, BC, Canada.
Dr. Michelle Chang (Ph.D. 2015)
Thesis title: “Biochemical and Biophysical Investigations of N-linked Glycosylation Pathways in Archaea”
Synthetic Biologist, Asimov, Cambridge, MA.
Dr. Carsten Kroll (Postdoctoral Associate 2012-2014)
Research Scientist, F. Hoffman-La Roche Ltd, Basel, Switzerland.
Dr. Silvano Sanchini (Postdoctoral Associate (2014-2016)
Scientist in Protein Chemistry, LI-COR, Lincoln, NE.
Dr. Laura Peterson (Postdoctoral Associate 2012-2014)
Instructor, University of Florida, Gainesville, FL.
Stephanie Cheung (M.S. 2014)
Thesis title: “Development of fluorogenic biosensors for dynamic detection of cytokines”
Graduate Student, EMBL-Heidelberg, Ikmi lab, Germany.
Dr. Andrew Krueger (Postdoctoral Associate 2009-2013)
Investigator, Novartis Institute for Biomedical Research, Cambridge, MA.
Dr. Michael J. Morrison (Ph.D. 2013)
Thesis title: "Elucidation of the pathways responsible for the biosynthesis of UDP-N,N’-diacetylbacillosamine in bacterial pathogens."
Director, Rheos Medicines, Cambridge, MA.
Dr. Marcie Jaffee (Ph.D. 2013)
Thesis title: "Investigation of the Structural Requirements for Oligosaccharyl Transferase Function."
Biochemistry Fellow, Centers for Disease Control and Prevention, Atlanta, GA.
Dr. Elke Piper (Socher) (Postdoctoral Associate 2010-2013)
Senior Research Scientist at Federal Institute of Risk Assessment (BfR), Berlin, Germany
Dr. Philipp Schneggenburger (Postdoctoral Associate 2010-2013)
Associate Director, Intellia Therapeutics, Cambridge MA
Dr. Meredith Hartley (Ph.D. 2011)
Thesis title: "Polyprenyl-dependent glycan assembly pathways in microbial pathogens."
Postdoctoral Associate with Dr. Tom Scanlan, Dept. of Physiology and Pharmacology, Oregon Health and Science University, Portland, OR.
Dr. Brenda Goguen (Ph.D. 2011)
Thesis title: "Development and Application of Chemical Tools for Investigating Dynamic Processes in Cell Migration."
Manager, Clarion Healthcare Consulting, Boston, MA.
Dr. Cliff Stains (Postdoctoral Associate 2008-2011)
Associate Professor, University of Nebraska - Lincoln, Lincoln, NE. (http://chem.unl.edu/faculty/cstains.shtml)
Dr. James Morrison (Postdoctoral Associate 2008-2011)
Investigator, GlaxoSmithKline, Upper Merion, PA.
Dr. Wendy Iskenderian-Epps (Ph.D. 2011)
Thesis title: "Mapping the Synapse: Synthesis and Validation of Chemical Probes for Interrogating PDZ Domains."
Lecturer, Dartmouth College, Hanover, NH.
Dr. Angelyn Larkin (Ph.D. 2010)
Thesis title: "Investigation of Asparagine-Linked Glycosylation in Archaeal and Bacterial Systems."
Patent Agent/Technology Specialist at Lando & Anastasi, LLP, Boston, MA.
Dr. Daniel Jiménez Teja (Postdoctoral Associate 2009-2010)
Research Scientist, Lopez-Neyra Parasitology and Biomedicine Institute (IPBLN), Grenada, Spain.
Dr. Jerry Troutman (Postdoctoral Associate 2006-2010)
Associate Professor, University of North Carolina - Charlotte, Charlotte, NC. (http://chemistry.uncc.edu/faculty/131-troutman-jay-m.html)
Dr. Nelson Olivier (Postdoctoral Associate 2005-2009)
Associate Director of Innovative Medicines Biotech Unit, AstraZeneca, Waltham, MA.
Dr. Matthieu Sainlos (Postdoctoral Associate 2004-2009)
Independent Researcher, National Center for Scientific Research (CNRS), Bordeaux, France.
Dr. Galen Loving (Ph.D. 2009)
Thesis title: "New Tools Derived from the Solvatochromic 4-N,N-Dimethylamino-1,8-naphthalimide Fluorophore for the Detection of Biomolecular Interactions."
Scientist, Carmot Therapeutics, San Francisco, CA.
Dr. Elvedin Lukovic (Ph.D. 2009)
Thesis title: "Development of Selective Peptide and Protein-Based Reporters of Kinase Activity Utilizing Chelation-Enhanced Fluorescence." Assistant Attending and Fellow in Critical Care Medicine at Fellow in Critical Care Medicine, Columbia University Medical Center, New York, NY.
Dr. Mark Chen (Ph.D. 2009)
Thesis title: "Investigating Asparagine-Linked Glycosylation Substrate Specificity and Effects on Protein Folding."
Manager of Analytics Automation and Data at Mountain Equipment Coop, Vancouver BC, Canada.
Dr. Juan Antonio González Vera (Postdoctoral Associate 2006-2008)
Research Scientist, Medicinal Chemistry Institute, Spanish Research Council (CSIC), Madrid, Spain.
Dr. Anne Reynolds (Postdoctoral Associate 2005-2008)
Intellectual Property Attorney at Casimir Jones, S.C. Madison, WI.
Dr. Langdon Martin (Ph.D. 2008)
Thesis title: "Development of Lanthanide-Binding Tags (LBTs) as Powerful and Versatile Peptides For Use in Studies of Proteins and Protein Interactions."
Professor of Chemistry, Warren Wilson College, Asheville, NC. (http://www.warren-wilson.edu/includes/staff_bios.php?user=lmartin)
Dr. Melanie Bonnekessel (Postdoctoral Associate 2007-2008)
Chemist, BASF, Ludwigshafen, Germany.
Dr. Andreas Aemissegger (Postdoctoral Associate 2005-2007)
Director of Production at Bachem AG, Basel, Switzerland
Dr. Dora Carrico-Moniz (Postdoctoral Associate 2004-2007)
Associate Professor, Wellesley College, Wellesley, MA. (http://www.wellesley.edu/Chemistry/Dora/index.html)
Dr. Elizabeth Taylor (Vogel) (Ph.D. 2006)
Thesis title: "Caged Phosphopeptides and Phosphoproteins: Probes to Dissect the Role of Phosphorylation in Complex Signaling Pathways."
Lecturer, CONCOURSE,, Massachusetts Institute of Technology, Cambridge, MA.
Dr. Seungjib Choi (Ph.D. 2006)
Thesis title: "Development of Transition State Analogues Targeting Chitinases and Oligosaccharyl Transferase."
Research Scientist, Samsung, South Korea.
Dr. Bianca Sculimbrene (Postdoctoral Associate 2004-2006)
Associate Professor, College of the Holy Cross, Worcester, MA. (http://college.holycross.edu/faculty/bsculimb/)
Dr. Guofeng Zhang (Postdoctoral Associate 2003-2006)
Research Scientist, GlaxoSmithKline, King of Prussia, PA.
Dr. Kerney Jebrell Glover (Postdoctoral Associate 2001-2006)
Associate Professor, Lehigh University, West Bethlehem, PA. (http://cas.lehigh.edu/casweb/content/default.aspx?pageid=526)
Dr. Mary O'Reilly (Ph.D. 2006)
Thesis title: "Investigating the Pathway of Asparaginen-Linked Glycoprotein Biosynthesis."
Freelance Science Illustrator and Animator, O’Reilly Science Art, LLC, La Jolla, CA. (http://www.oreillyscienceart.com/)
Dr. Eranthie Weerapana (Ph.D. 2006)
Thesis title: "Investigating Asparagine-Linked Protein Glycosylation in Eukaryotic and Prokaryotic Systems."
Associate Professor, Boston College, Boston, MA. (http://www.bc.edu/schools/cas/chemistry/faculty/weerapana.html)
Dr. Christian Hackenberger (Postdoctoral Associate 2003-2005)
Leibniz-Humboldt Professor for Chemical Biology, Leibniz-Institute for Molecular Pharmacology (FMP), Berlin, Germany. (www.fmp-berlin.info/hackenbe/)
Dr. Deborah Rothman (Ph.D. 2005)
Thesis title: "Caged Phosphopeptides and Phosphoproteins: Agents in Unraveling Complex Biological Pathways."
Director, Chemical Biology, Merck Kenilworth, NJ.
Dr. Melissa Shults Won (Ph.D. 2005)
Thesis title: "Chemosensing Strategies Utilizing the Novel Sulfonamidohydroxyquinoline Amino Acid Sox."
Vice President, Arima Genomics, San Diego, CA.
Dr. Christina Carrigan (Postdoctoral Associate 2003-2005)
R&D Scientist, Biomarkers, San Francisco, CA.
Dr. Mayssam Ali (Ph.D. 2004)
Thesis title: "Design and Structural Characterization of Oligomeric ßßa Mini-Proteins."
Associate, Finnegan, Henderson, Farabow, Garrett & Dunner, LLP, Cambridge, MA.
Dr. M. Eugenio Vazquez (Postdoctoral Associate 2001-2004)
Profesor Titular, Dept. of Organic Chemistry, University of Santiago de Compostela, Spain. (http://web.usc.es/~eugeniov/index.html)
Dr. Mark Nitz (Postdoctoral Associate 2001-2004)
Professor and Associate Chair, University of Toronto, Canada. (www.chem.utoronto.ca/staff/mnitz/mn/index.html)
Dr. Katherine Franz (Postdoctoral Associate 2000-2003)
Alexander F. Hehmeyer Professor of Chemistry, Duke University, Durham, NH. (http://chem.duke.edu/faculty/katherine-j-franz)
Dr. Carlos Bosques (Ph.D. 2003)
Thesis title: "Effects of Glycosylation on the Structure and Fibrillization of Prion Protein Fragments."
Vice President of R&D and Innovation at Evolved By Nature, Arlington, MA
Dr. Maria Ufret (Ph.D. 2003)
Thesis title: "Studies Towards In Vivo Inhibition of Oligosaccharyl Transferase."
Principal Scientist, IPSEN Bioscience, Inc., Cambridge, MA.
Dr. Robert Dempski (Ph.D. 2003)
Thesis title: "Investigation of the Yeast Oligosaccharyl Transferase."
Assiociate Professor, Worcester Polytechnic Institute, Worcester, MA. (http://www.wpi.edu/Pubs/Faculty/red.html)
Soonsil Hyun (M.S. 2003)
Thesis title: "Design and Photochemical Properties of Caged Zn2+: Chelators Bind Zn2+ with High Affinity and Release it upon Photolysis."
Dr. Harm Brummerhop (Postdoctoral Associate 2001)
Scientist, Aventis Pharm, Germany.
Dr. Dierdre Pearce (Postdoctoral Associate 1997-2001)
Project Manager, Australian National University, Canberra, Australia.
Dr. Kevin McDonnell (Ph.D. 2001)
Thesis title: "Incorporation of Catalytic Function into Folded Polypeptide Scaffold."
Director of Targeting Chemistry, BIND Biosciences, Cambridge, MA.
Dr. Jennifer Ottesen (Ph.D. 2001)
Thesis title: "Design of Descretely Folded Mini-Protein Motifs."
Associate Professor, Ohio State University, Columbus, OH. (http://www.biosci.ohio-state.edu/~biochem/faculty/Ottesen.html)
Dr. Sarah E. O'Connor (Ph.D. 2001)
Thesis title: "Conformational Effects of Asparagine-Linked Glycosylation."
Professor and Project Leader, The John Innes Centre and the University of East Anglia, Norwich UK. (www.uea.ac.uk/chemistry/people/profile/sarah-oconnor)
Dr. Adam Mezo (Postdoctoral Associate 1999-2000)
Senior Director, and Head of Molecular Design, Ferring Pharmaceuticals, San Diego, CA.
Dr. Nathalie Jotterand (Postdoctoral Associate 1999-2000)
Research Associate, Novartis Pharma AG, Basel, Switzerland.
Dr. Stephane Peluso (Postdoctoral Associate 1999-2000)
Global Head of Oncology External Innovation at IPSEN, Boston, MA.
Dr. Vincent Tai (Ph.D. 2001)
Thesis title: "Mechanistic studies of Oligosaccharyl Transferase Employing Synthetic Inhibitor and Substrate Analogues."
Investigator, GlaxoSmithKline, Research Triangle Park, NC.
Dr. Peter Soderman (Postdoctoral Associate 1999-2000)
Innovation Program Manager at the Karolinska University Hospital, Stockholm, Sweden.
Dr. Michael Shogren-Knaak (Ph.D. 2000)
Thesis title: "Incorporating Functions into BBA Peptide Motifs."
Associate Professor, Iowa State University, Ames, IA. (http://www.bbmb.iastate.edu/shogren-knaak.shtml)
Dr. Paula Eason (Postdoctoral Associate 1997-2000)
Director of Medical Alignment, Lung Cancer, Medical Affairs at Astra Zeneca, Washington DC.
Dr. Jens Pohlmann (Postdoctoral Associate 1997-1998)
Medicinal Chemistry Consultant, Basel, Switzerland.
Dr. Jean Ernest Sohna Sohna (Postdoctoral Associate 1997-1998)
Director, Vanga lama, Ltd. Norwich, UK
Dr. Kazuaki Kudo (Postdoctoral Associate 1997-1998)
Professor, Institute of Industrial Science, University of Tokyo, Japan.
Dr. Grant Walkup (Ph.D. 1998)
Thesis title: "Fluorescent Peptidyl Chemosensors for the Measurement of Divalent Metal Cation Concentrations."
Director of Biochemistry, Agios Pharmaceuticals, Cambridge, MA.
Dr. Richard Ping Cheng (Ph.D. 1998)
Thesis title: "Design and Synthesis of Metallopeptides; Incorporation of Unnatural alpha-Amino Acids and Construction of a Structural Template."
Professor of Chemistry,, National Taiwan University, Taiwan. (http://www.ch.ntu.edu.tw/english/faculty/rpcheng-e.html)
Dr. Christine Davis Rener (Postdoctoral Associate 1995-1997)
Vice Provost for Instructional Development and Innovation and Director of the Pew Faculty Teaching & Learning Center, Grand Valley State University (https://www.gvsu.edu/chem/christine-rener-120.htm)
Dr. Christine Kellenberger (Postdoctoral Associate 1996-1997)
Research Fellow, AFMB-CNRS, Marseille, France.
Dr. Rahul Pathak (Ph.D. 1997)
Thesis title: "The Saccharomyces cerevisiae Oligosaccharyl Transferase.”
Partner, Squire, Patton and Boggs, San Francisco, CA.
Dr. Ming C. Hammond (Undergraduate Research 1996-1999)
Associate Professor of Chemistry, University of Utah, Salt Lake City, UT
Dr. Alicia Torrado (Postdoctoral Associate 1994-1996)
Principal Research Scientist, Lilly S. A., Madrid, Spain.
Dr. Tamara Lynn Hendrickson (Ph.D. 1996)
Thesis title: "Insights into the Mechanism of Asparagine-Linked Glycosylation: Kinetic Studies with Substrates and Inhibitors."
Associate Professor, Wayne State University, Detroit, OH. (http://chem.wayne.edu/faculty/hendrickson/)
Dr. Ranabir Sinha Roy (Ph.D. 1996)
Thesis title: "Coenzyme-amino Acid Chimeras: New Residues for the Design of Functional Proteins.
Sr. Director and Compound Development Team Leader, Janssen Research & Development, Johnson & Johnson, Raritan, NJ.
Dr. Mary Denise Struthers (Ph.D. 1996)
Thesis title: "Structural Templates for Protein Design: The Assembly of Peptidyl Motifs with Defined Supersecondary Structure."
Director Immunoscience at Bristol-Myers Squibb, Lawrenceville, NJ.
Dr. William Dvorak Shrader (Postdoctoral Associate 1994-1996)
Fellow at BioElectron Technology Corporation, Mountain View CA
Dr. Keith Warren Rickert (Ph.D. 1996)
Thesis title: "Protein Glycosylation: Substrate Selectivity and Conformational Consequences."
Senior Research Scientist, Medimmune, Gaithersburg, MD
Dr. Lisa Wang (Postdoctoral Associate 1993-1995)
Senior Product Manager, Clinical and Educational Microscopes, Olympus America, Inc. Waltham, MA.
Dr. Jeffrey Spencer (Postdoctoral Associate 1993-1995).
Founder and CEO at STRATEGICS Inc. South San Francisco, CA
Dr. Stewart Lindsay Fisher (Ph.D. 1993)
Thesis title: "Unnatural Amino Acids in the Synthesis and Semisynthesis of Metalloprotein Motifs."
Chief Scientific Officer at C4 Therapeutics, Inc. Cambridge, MA.
Dr. Tarun Kapoor (Undergraduate Researcher 1989-1993)
PELS Family Professor, The Rockefeller University, New York, NY.
Dr. Karen L. (Mrksich) Shannon Mrksich (Ph.D. 1992)
Thesis title: "Conformational and Mechanistic Studies of Asparagine-Linked Glycosylation."
VP, Intellectual Property at Beckman Coulter, La Brea, CA.
Thomas Prins (M.S. 1992)
Thesis title: "Synthesis of Unnatural Amino Acids with Chelating Side Chains and the Characterization of Peptides Incorporating them."
Kalypsys, San Diego, CA.
Dr. Masafumi Unno (Postdoctoral Associate 1991-1992)
Professor, Gunma University, Japan. (http://element.chem-bio.st.gunma-u.ac.jp/index-e.html)
Dr. Rex A. Moats (Postdoctoral Associate 1990-1992)
Assistant Professor Research, Childrens Hospital, Los Angeles / University of Southern California, Los Angeles, CA.
Dr. Janet Warren Zimmerman (Ph.D. 1990, Carnegie Mellon University)
Thesis title: "Investigation of the Initial Steps of Asparagine- Linked Glycosylation."
Group leader (Scientist I) in the Glycobiology group at Alpha-Beta Technology, Worcester, MA.